Causes of Psoriatic Arthritis

Psoriatic arthritis is a type of inflammatory arthritis that affects some people with psoriasis, a chronic autoimmune skin condition characterized by red, scaly patches on the skin.

Main causes of Psoriatic Arthritis

The exact cause of psoriatic arthritis is not fully known, but it is believed to involve a combination of genetic, immune system, and environmental factors. Here are some key factors thought to contribute to the development of psoriatic arthritis:

Genetics: Psoriatic arthritis tends to run in families, suggesting a genetic predisposition to the condition. Certain genes, such as those associated with the immune system, may increase the risk of developing psoriatic arthritis.

Immune System Dysfunction: Psoriatic arthritis is considered an autoimmune disease, which means that the body's immune system mistakenly attacks its own tissues. In psoriatic arthritis, the immune system targets the joints, leading to inflammation and tissue damage.

Psoriasis: Many people with psoriatic arthritis also have psoriasis, although not everyone with psoriasis develops psoriatic arthritis. Psoriasis typically precedes the onset of psoriatic arthritis, with joint symptoms usually appearing months or years after skin symptoms.

Environmental Triggers: Certain environmental factors, such as infections or injuries, may trigger the development of psoriatic arthritis in individuals who are genetically predisposed to the condition. Infections, particularly streptococcal infections, are thought to be potential triggers for psoriasis and psoriatic arthritis in some cases.

Inflammation: Chronic inflammation plays a central role in the development and progression of psoriatic arthritis. Inflammation in the joints and surrounding tissues leads to pain, stiffness, swelling, and damage to the affected joints over time.

Lifestyle Factors: Lifestyle factors such as smoking, obesity, and stress may also contribute to the development or worsening of psoriatic arthritis in some individuals.

It's important to note that while these factors are associated with psoriatic arthritis, the exact mechanisms underlying the disease are still being studied. Additionally, not everyone with psoriasis will develop psoriatic arthritis, and the severity and progression of the condition can vary widely among individuals. Early diagnosis and treatment are important for managing symptoms and preventing joint damage in people with psoriatic arthritis. If you have psoriasis and are experiencing joint pain or other symptoms suggestive of psoriatic arthritis, it's essential to see a healthcare professional for an accurate diagnosis and appropriate treatment.

Causes of Psoriatic Arthritis

Dr Vishad Viswanath's IRIS Centre is a dedicated institute for advanced treatment of all kinds of rheumatic problems. We aim to provide state of the art care in rheumatic diseases with at most sincerity and compassion. 

IRIS Centre for Arthritis & Rheumatology

Malayil Centre
Chenthi
Pongumoodu
Thiruvananthapuram, Kerala 695011

Contact Number: +91 471 2412573; +91 8281445394



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Causes of Psoriatic Arthritis

Psoriatic arthritis is a type of inflammatory arthritis that affects some people with psoriasis, a chronic autoimmune skin condition charact...